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hsa-mir-708

Summary

Mirbase symbol:
hsa-mir-708
Gene type:
miscRNA
Mirbase accession:
MI0005543
Summary:
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Genomic context

Chromosome:
chr11
Strand:
-
Start:
79402022
End:
79402109
Intragenic:
Yes
Region:
Intronic
Intron number:
1
Distance from 5' exon:
38400
hsa-mir-708: chromosome chr11 (-) length: 87 bp 5' - (79,402,022) (79,402,109) - 3' click here to browse this region (-chr11:79402022-79402109) to get detailed information on - conservation - histone marks - SNPs - Low complexity regions - ... UCSC Genome Browser CAACUAGACUGUGAGCUUCUAG hsa-miR-708-3p hsa-miR-708-3p AAGGAGCUUACAAUCUAGCUGGG hsa-miR-708-5p hsa-miR-708-5p aactgccctcaaggagcttacaatctagctgggggtaaatgacttgcacatgaacacaactagactgtgagcttctagagggcaggga

Host gene information

Gene Host gene type Entrez gene ID Direction
TENM4 protein-coding 26011 sense
TENM4: chromosome chr11 (-) length: 787,736 bp 5' - (78,653,283) (79,441,019) - 3' Summarized Transcript Annotation click here to browse this region (-chr11:78653283-79441019) to get detailed information on - conservation - histone marks - SNPs - Low complexity regions - ... UCSC Genome Browser Individual RefSeq Samples XM_017017525 NM_001098816 XM_017017526 XM_011544933 hsa-mir-708 hsa-mir-5579

miRNA Expression

There are no expression data for hsa-mir-708 in our database.

Expression correlation between miRNA and Host gene

mRNA expression in TCGA samples (cancer and normal samples)

Here we have a boxplot that shows how this miRNA is expressed in different tumor contexts. We have a plot for each sample type (normal, metastatic and tumor).

Here we have a table with miRNA expression in tumor, metastatic and normal tissue.

miRNA Symbol Sample Type Average RPM (Reads Per Million) TCGA Project TCGA Acronym Meaning
Gene Sample Type Average Gene Expression miRNA Symbol Average miRNA Expression TCGA Project TCGA Acronym Meaning

Potential gene targets

The table shows gene targets predicted by seed match (8mer,7mer-m8,7mer-1A) according to TargetScan 6.2.

There are no gene targets for hsa-mir-708 predicted by TargetScan 6.2.